Research Needs Rodent Models of Restless Legs Syndrome, But Assessing RLS in Mice Is Tricky

The International Restless Legs Syndrome Study Group publishes a new guideline on construct validity of rodent models of RLS. By Jane Kollmer How do you know if a mouse has restless legs syndrome? It’s a seemingly strange question, but one that is essential to restless legs syndrome (RLS) research because before studies can be conducted … Read more

Don’t Light the Fuse of Restless Legs Syndrome with Dopamine Agonists

Twenty percent of restless legs syndrome patients are already on higher-than-recommended doses of dopamine agonists, says John Winkelman, MD, PhD. By Bushraa Khatib Starting a dopamine agonist to treat restless legs syndrome (RLS) is like lighting a fuse, with the near certainty that at some point in the future, the medication will cause RLS symptoms … Read more